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Variants of type 1 diabetes

 Type 1 diabetes and its variants.

Some years ago when I started this blog, I wrote about diabetes and also about my history of being diagnosed with type 1 diabetes, this time I want to share with you the variants or the classification that exists within this type of diabetes.


Concepts.

Before going fully into the variants, I think it is important to remember the concepts of diabetes and type 1 diabetes:

Diabetes: is a chronic condition that appears when the pancreas is not able to produce enough insulin or when the body cannot use the insulin it produces. It is mainly characterized by the presence of high concentrations of glucose in the blood (hyperglycemia).

Type 1 diabetes: is an autoimmune disease, in which the insulin-producing cells are attacked and destroyed: the beta cells of the pancreas. Lacking insulin, the metabolism of carbohydrates, fats, and proteins cannot be carried out correctly. Better known as insulin-dependent or juvenile diabetes mellitus.



Variants of type 1 diabetes.

Having these two concepts, let's now continue with the variants that occur within type 1 diabetes.

In type 1 diabetes, two fundamental variants are distinguished:

Type 1a diabetes mellitus, which is of autoimmune origin, and type 1b diabetes mellitus, which is idiopathic.

Autoimmune diabetes: is an autoimmune disorder in which the body's immune system attacks the beta cells of the pancreas that produce insulin. This is the most common type of type 1 diabetes and results from the interaction of environmental and genetic factors.

Type 1 idiopathic diabetes: This refers to rare forms of the disease for which there is no known cause. Initial insulinogenic, the tendency to ketosis or ketoacidosis is present, in which no data of autoimmunity are found. Idiopathic diabetes is more common in the African American, Asian, and Hispanic American populations.


It is very important to know that the origin and causes of diabetes mellitus can be very diverse, but it entails the existence of alterations in insulin secretion, sensitivity to the action of the hormone, or both at some point in its natural history.




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